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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:O15075

DCLK1

Protein·UNIPROT:O15075

Open in the graph

Probable kinase that may be involved in a calcium-signaling pathway controlling neuronal migration in the developing brain. May also participate in functions of the mature nervous system.

Function from UniProtKB (O15075), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

6 statements

6 statements · 1 reference database · Subject: DCLK1 · Sources: Hetionet

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PRKX covaries with DCLK1ProteinHetionet hetionet:covaries:5613-9201Inferred only
DCLK1 decreases the expression of CDKN1BProteinHetionet hetionet:regulates:9201-1027Inferred only
CLTB increases the expression of DCLK1ProteinHetionet hetionet:regulates:1212-9201Inferred only
DCLK1 increases the expression of S100A2ProteinHetionet hetionet:regulates:9201-6273Inferred only
DCLK1 increases the expression of WFS1ProteinHetionet hetionet:regulates:9201-7466Inferred only
DCLK1 increases the expression of WIF1ProteinHetionet hetionet:regulates:9201-11197Inferred only

Reactions

2 reactions

L-seryl-[protein]+ATP(4-)O-phospho-L-seryl-[protein]+ADP(3-)+hydron
Catalysed by SGK1 or CDC7 or PLK4 or STK25 or CIT or RIOK3 or MAP2K7 or CHEK1 or BCKDK or IKBKB or CASK or AURKA and 347 more alternatives
Reaction pageLeft to right

Other names

6 names

Resolves to: DCLK1

Also called: DCAMKL1DCDC3ADoublecortin domain-containing protein 3ADoublecortin-like and CAM kinase-like 1Doublecortin-like kinase 1KIAA0369

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Balance undeterminable

Rhea RHEA:17989CC BY 4.0Reference data

L-threonyl-[protein]+ATP(4-)O-phospho-L-threonyl-[protein]+ADP(3-)+hydron

Catalysed by SGK1 or CDC7 or PLK4 or STK25 or CIT or RIOK3 or MAP2K7 or CHEK1 or IKBKB or CASK or AURKA or GAK and 341 more alternatives

Reaction pageLeft to rightBalance undeterminable

Rhea RHEA:46608CC BY 4.0Reference data