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Proteins/UNIPROT:Q8NFT6
Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S and M phases. The complex CDC7-DBF4B selectively phosphorylates MCM2 subunit at 'Ser-40' and then is involved in regulating the initiation of DNA replication during cell cycle..
Function from UniProtKB (Q8NFT6), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
8 statements
8 statements · 2 reference databases · Subject: DBF4B · Sources: gene ontology, Hetionet
6 names
Resolves to: DBF4B