Proteins/UNIPROT:O43739

CYTH3

ProteinUNIPROT:O43739

Promotes guanine-nucleotide exchange on ARF1 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays a role in the epithelial polarization (By similarity)..

Function from UniProtKB (O43739), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

16 statements

16 statements · 4 reference databases · Subject: CYTH3 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

EN2 covaries with CYTH3ProteinHetionet hetionet:covaries:2020-9265Inferred only
CYTH3 covaries with NSG1ProteinHetionet hetionet:covaries:27065-9265Inferred only
CYTH3 interacts with CALCOCO1ProteinHetionet hetionet:interacts:57658-9265Inferred only
CYTH3 interacts with CNKSR1ProteinHetionet hetionet:interacts:10256-9265Inferred only
CYTH3 interacts with CYTIPProteinHetionet hetionet:interacts:9265-9595Inferred only
CYTH3 interacts with FRMD4BProteinHetionet hetionet:interacts:23150-9265Inferred only
CYTH3 interacts with IPCEF1ProteinHetionet hetionet:interacts:26034-9265Inferred only
CYTH3 interacts with TAMALINProteinHetionet hetionet:interacts:160622-9265Inferred only
UBC interacts with CYTH3ProteinHetionet hetionet:interacts:7316-9265Inferred only
CYTH3 participates in 2q37 copy number variation syndromePathwayWikiPathways WP5224Inferred only
CYTH3 participates in Insulin signalingPathwayWikiPathways WP481Inferred only
CYTH3 participates in Intra-Golgi and retrograde Golgi-to-ER trafficPathwayReactome R-HSA-6811442Inferred only

Show the remaining 4

CYTH3 participates in Intra-Golgi trafficPathwayReactome R-HSA-6811438Inferred only
CYTH3 participates in Membrane TraffickingPathwayReactome R-HSA-199991Inferred only
CYTH3 participates in Vesicle-mediated transportPathwayReactome R-HSA-5653656Inferred only
CYTH3 regulates regulation of ARF protein signal transductionBiological processgene ontology O43739|GO:0032012Inferred only

Other names

7 names

Resolves to: CYTH3

Also called: ARF nucleotide-binding site opener 3ARNO3General receptor of phosphoinositides 1GRP1PH, SEC7 and coiled-coil domain-containing protein 3Protein ARNO3PSCD3

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