Proteins/UNIPROT:Q9BQA9

CYBC1

ProteinUNIPROT:Q9BQA9

Functions as a chaperone necessary for a stable expression of the CYBA and CYBB subunits of the cytochrome b-245 heterodimer. Controls the phagocyte respiratory burst and is essential for innate immunity (By similarity)..

Function from UniProtKB (Q9BQA9), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

2 rows

chronic granulomatous disease has a germline basis in CYBC1DiseaseGenCC HGNC:28672|MONDO:0018305Inferred only
granulomatous disease, chronic, autosomal recessive, 5 has a germline basis in CYBC1DiseaseGenCC HGNC:28672|MONDO:0030066Inferred only

Statements

11 statements

11 statements · 2 reference databases · Subject: CYBC1 · Sources: Hetionet, WikiPathways

Order

CYBC1 covaries with DUS1LProteinHetionet hetionet:covaries:64118-79415Inferred only
CYBC1 covaries with IL17RELProteinHetionet hetionet:covaries:400935-79415Inferred only
ETS1 interacts with CYBC1ProteinHetionet hetionet:interacts:2113-79415Inferred only
UBC interacts with CYBC1ProteinHetionet hetionet:interacts:7316-79415Inferred only
CYBC1 participates in Genetic causes of porto sinusoidal vascular diseasePathwayWikiPathways WP5269Inferred only
ATG5 decreases the expression of CYBC1ProteinHetionet hetionet:regulates:9474-79415Inferred only
EGFR decreases the expression of CYBC1ProteinHetionet hetionet:regulates:1956-79415Inferred only
FOS decreases the expression of CYBC1ProteinHetionet hetionet:regulates:2353-79415Inferred only
H2BC21 decreases the expression of CYBC1ProteinHetionet hetionet:regulates:8349-79415Inferred only
ILK increases the expression of CYBC1ProteinHetionet hetionet:regulates:3611-79415Inferred only
PSIP1 increases the expression of CYBC1ProteinHetionet hetionet:regulates:11168-79415Inferred only

Other names

3 names

Resolves to: CYBC1

Also called: C17orf62EROSEssential for reactive oxygen species protein

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