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Proteins/UNIPROT:Q2TBE0
RNA-binding protein which regulates alternative splicing (By similarity). Recognizes the 5'-GG[A/C][A/G]G[A/C/G]-3' motif with 58% of target sequences containing a 5'-GGCAGA-3' motif (By similarity). Directly binds and regulates the splicing of genes related to spermatogenesis such as ZNHIT1, BTRC and FBXW7 and is thus required for male fertility (By similarity). Also has an indirect effect on splicing by acting on the splicing factor RBFOX1 (By similarity). Required for spliceosome assembly and stability (By similarity). Required for debranching of intron-derived lariat RNAs..
Function from UniProtKB (Q2TBE0), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
6 statements
6 statements · 2 reference databases · Subject: CWF19L2 · Sources: Hetionet, Reactome
2 names
Resolves to: CWF19L2