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Proteins/UNIPROT:P15509

CSF2RA

Protein·UNIPROT:P15509

Open in the graph

Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.

Function from UniProtKB (P15509), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

2 rows

hereditary pulmonary alveolar proteinosis has a germline basis in CSF2RADiseaseGenCC HGNC:2435|MONDO:0012580Inferred only
surfactant metabolism dysfunction, pulmonary, 4 has a germline basis in CSF2RADiseaseGenCC HGNC:2435|MONDO:0010424Inferred only

Statements

33 statements

33 statements · 4 reference databases · Subject: CSF2RA · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Search this listOrder

CHUK interacts with CSF2RAProteinHetionet hetionet:interacts:1147-1438Inferred only
CSF2 interacts with CSF2RAProteinHetionet hetionet:interacts:1437-1438Inferred only
CSF2RA interacts with CSF2RBProteinHetionet hetionet:interacts:1438-1439Inferred only
CSF2RA interacts with IKBKBProteinHetionet hetionet:interacts:1438-3551Inferred only
CSF2RA interacts with KITProteinHetionet hetionet:interacts:1438-3815Inferred only
CSF2RA interacts with LYNProteinHetionet hetionet:interacts:1438-4067Inferred only
CSF2RA interacts with PIK3R1ProteinHetionet hetionet:interacts:1438-5295Inferred only
CSF2RA interacts with RPSAProteinHetionet hetionet:interacts:1438-3921Inferred only
CSF2RA interacts with SDC2ProteinHetionet hetionet:interacts:1438-6383Inferred only
CSF2RA participates in Cancer pathwaysPathwayWikiPathways WP5434Inferred only
CSF2RA participates in Cell interactions in pancreatic cancer microenvironmentPathwayWikiPathways WP5284Inferred only
CSF2RA participates in Cytokine cytokine receptor interactionPathwayWikiPathways WP5473Inferred only

Show the remaining 21

CSF2RA participates in Cytokine Signaling in Immune systemPathwayReactome R-HSA-1280215Inferred only
CSF2RA participates in Defective CSF2RA causes SMDP4PathwayReactome R-HSA-5688890Inferred only
CSF2RA participates in Defective CSF2RB causes SMDP5PathwayReactome R-HSA-5688849Inferred only
CSF2RA participates in DiseasePathwayReactome R-HSA-1643685Inferred only
CSF2RA participates in Diseases associated with surfactant metabolismPathwayReactome R-HSA-5687613Inferred only
CSF2RA participates in Diseases of metabolismPathwayReactome R-HSA-5668914Inferred only
CSF2RA participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
CSF2RA participates in Interleukin receptor SHC signalingPathwayReactome R-HSA-912526Inferred only
CSF2RA participates in Interleukin-2 family signalingPathwayReactome R-HSA-451927Inferred only
CSF2RA participates in Interleukin-3, Interleukin-5 and GM-CSF signalingPathwayReactome R-HSA-512988Inferred only
CSF2RA participates in MAPK family signaling cascadesPathwayReactome R-HSA-5683057Inferred only
CSF2RA participates in MAPK1/MAPK3 signalingPathwayReactome R-HSA-5684996Inferred only
CSF2RA participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
CSF2RA participates in RAF/MAP kinase cascadePathwayReactome R-HSA-5673001Inferred only
CSF2RA participates in Regulatory circuits of STAT3 signalingPathwayWikiPathways WP4538Inferred only
CSF2RA participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
CSF2RA participates in Signaling by InterleukinsPathwayReactome R-HSA-449147Inferred only
CSF2RA participates in Surfactant metabolismPathwayReactome R-HSA-5683826Inferred only
CSF2RA regulates positive regulation of cell population proliferationBiological processgene ontology P15509|GO:0008284Inferred only
CSF2RA regulates positive regulation of leukocyte proliferationBiological processgene ontology P15509|GO:0070665Inferred only
CSF2RA regulates positive regulation of receptor signaling pathway via JAK-STATBiological processgene ontology P15509|GO:0046427Inferred only

Other names

7 names

Resolves to: CSF2RA

Also called: CD antigen CD116CDw116CSF2RCSF2RYGM-CSF-R-alphaGMCSFR-alphaGMR-alpha

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