Proteins/UNIPROT:Q86VX2

COMMD7

ProteinUNIPROT:Q86VX2

Scaffold protein in the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex. May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Associates with the NF-kappa-B complex and suppresses its transcriptional activity..

Function from UniProtKB (Q86VX2), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

7 statements

7 statements · 3 reference databases · Subject: COMMD7 · Sources: gene ontology, Hetionet, Reactome

Order

COMMD7 covaries with JOSD2ProteinHetionet hetionet:covaries:126119-149951Inferred only
COMMD7 interacts with COMMD1ProteinHetionet hetionet:interacts:149951-150684Inferred only
UBC interacts with COMMD7ProteinHetionet hetionet:interacts:149951-7316Inferred only
COMMD7 participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
COMMD7 participates in NeddylationPathwayReactome R-HSA-8951664Inferred only
COMMD7 participates in Post-translational protein modificationPathwayReactome R-HSA-597592Inferred only
COMMD7 regulates negative regulation of DNA-templated transcriptionBiological processgene ontology Q86VX2|GO:0045892Inferred only

Other names

2 names

Resolves to: COMMD7

Also called: C20orf92COMM domain-containing protein 7

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