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Reference

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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:Q96IL0

COA8

Protein·UNIPROT:Q96IL0

Open in the graph

Required for cytochrome c complex (COX) IV assembly and function Protects COX assembly from oxidation-induced degradation, COX being the terminal component of the mitochondrial respiratory chain..

Function from UniProtKB (Q96IL0), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

3 rows

mitochondrial complex IV deficiency, nuclear type 17 has a germline basis in COA8DiseaseGenCC HGNC:20492|MONDO:0033652Inferred only
mitochondrial disease has a germline basis in COA8DiseaseGenCC HGNC:20492|MONDO:0044970Inferred only
non-progressive predominantly posterior cavitating leukoencephalopathy with peripheral neuropathy has a germline basis in COA8DiseaseGenCC HGNC:20492|MONDO:0018576Inferred only

Statements

1 statement

1 statement · 1 reference database · Subject: COA8 · Sources: Hetionet

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UBC interacts with COA8ProteinHetionet hetionet:interacts:7316-84334Inferred only

Other names

5 names

Resolves to: COA8

Also called: APOP-1APOP1APOPT1Apoptogenic protein 1, mitochondrialC14orf153

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