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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:P34972

CNR2

Protein·UNIPROT:P34972

Open in the graph

Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis..

Function from UniProtKB (P34972), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

17 statements

17 statements · 4 reference databases · Subject: CNR2 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

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LEUTX covaries with CNR2ProteinHetionet hetionet:covaries:1269-342900Inferred only
SBK3 covaries with CNR2ProteinHetionet hetionet:covaries:100130827-1269Inferred only
ZNF239 covaries with CNR2ProteinHetionet hetionet:covaries:1269-8187Inferred only
CNR2 interacts with GNA15ProteinHetionet hetionet:interacts:1269-2769Inferred only
CNR2 participates in Cannabinoid receptor signalingPathwayWikiPathways WP3869Inferred only
CNR2 participates in Class A/1 (Rhodopsin-like receptors)PathwayReactome R-HSA-373076Inferred only
CNR2 participates in G alpha (i) signalling eventsPathwayReactome R-HSA-418594Inferred only
CNR2 participates in GPCR downstream signallingPathwayReactome R-HSA-388396Inferred only
CNR2 participates in GPCR ligand bindingPathwayReactome R-HSA-500792Inferred only
CNR2 participates in GPCRs class A rhodopsin likePathwayWikiPathways WP455Inferred only
CNR2 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
CNR2 participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only

Show the remaining 5

CNR2 participates in Small ligand GPCRsPathwayWikiPathways WP247Inferred only
CNR2 regulates negative regulation of action potentialBiological processgene ontology P34972|GO:0045759Inferred only
CNR2 regulates negative regulation of mast cell activationBiological processgene ontology P34972|GO:0033004Inferred only
CNR2 regulates negative regulation of synaptic transmission, GABAergicBiological processgene ontology P34972|GO:0032229Inferred only
CNR2 regulates positive regulation of osteoblast differentiationBiological processgene ontology P34972|GO:0045669Inferred only

Other names

6 names

Resolves to: CNR2

Also called: CB-2CB2CB2ACB2BCX5hCB2

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