Proteins/UNIPROT:Q9HAE3

CLXN

ProteinUNIPROT:Q9HAE3

Component of the outer dynein arm-docking complex (ODA-DC) that mediates outer dynein arms (ODA) binding onto the doublet microtubule. Seems to regulate the assembly of both ODAs and their axonemal docking complex onto ciliary microtubules (By similarity). Regulates ciliary and flagellar motility and is required for cilia-driven determination of body laterality (By similarity)..

Function from UniProtKB (Q9HAE3), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

ciliary dyskinesia, primary, 53 has a germline basis in CLXNDiseaseGenCC HGNC:25678|MONDO:0957991Inferred only

Statements

4 statements

4 statements · 2 reference databases · Subject: CLXN · Sources: gene ontology, Hetionet

Order

CLXN covaries with ZNF10ProteinHetionet hetionet:covaries:7556-79645Inferred only
CLXN regulates regulation of cilium movementBiological processgene ontology Q9HAE3|GO:0003352Inferred only
CLXN regulates regulation of flagellated sperm motilityBiological processgene ontology Q9HAE3|GO:1901317Inferred only
CLXN regulates regulation of signal transductionBiological processgene ontology Q9HAE3|GO:0009966Inferred only

Other names

4 names

Resolves to: CLXN

Also called: CalaxinEF-hand calcium-binding domain-containing protein 1EFCAB1ODAD5

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