Proteins/UNIPROT:Q6UXN8

CLEC9A

ProteinUNIPROT:Q6UXN8

Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner..

Function from UniProtKB (Q6UXN8), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

2 statements

2 statements · 2 reference databases · Subject: CLEC9A · Sources: gene ontology, Hetionet

Order

CYGB covaries with CLEC9AProteinHetionet hetionet:covaries:114757-283420Inferred only
CLEC9A regulates positive regulation of cytokine productionBiological processgene ontology Q6UXN8|GO:0001819Inferred only

Other names

2 names

Resolves to: CLEC9A

Also called: C-type lectin domain family 9 member ACD antigen CD370

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