Proteins/UNIPROT:Q92478

CLEC2B

ProteinUNIPROT:Q92478

Membrane-bound protein expressed on myeloid cells which acts as a ligand to stimulate the activating receptor NKp80/KLRF1, expressed on the surface of natural killer (NK) cells. In turn, stimulates NK-cell cytotoxicity and cytokine production leading to the cytolysis of malignant CLEC2B-expressing myeloid cells..

Function from UniProtKB (Q92478), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

4 statements

4 statements · 2 reference databases · Subject: CLEC2B · Sources: Hetionet, Reactome

Order

APP interacts with CLEC2BProteinHetionet hetionet:interacts:351-9976Inferred only
CLEC2B participates in Adaptive Immune SystemPathwayReactome R-HSA-1280218Inferred only
CLEC2B participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
CLEC2B participates in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellPathwayReactome R-HSA-198933Inferred only

Other names

6 names

Resolves to: CLEC2B

Also called: Activation-induced C-type lectinAICLC-type lectin superfamily member 2CLECSF2IFN-alpha-2b-inducing-related protein 1IFNRG1

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