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Proteins/UNIPROT:P08912

CHRM5

Protein·UNIPROT:P08912

Open in the graph

The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

Function from UniProtKB (P08912), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

14 statements

14 statements · 4 reference databases · Subject: CHRM5 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

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CHRM5 interacts with GPRASP1ProteinHetionet hetionet:interacts:1133-9737Inferred only
CHRM5 participates in Amine ligand-binding receptorsPathwayReactome R-HSA-375280Inferred only
CHRM5 participates in Calcium regulation in cardiac cellsPathwayWikiPathways WP536Inferred only
CHRM5 participates in Class A/1 (Rhodopsin-like receptors)PathwayReactome R-HSA-373076Inferred only
CHRM5 participates in G alpha (q) signalling eventsPathwayReactome R-HSA-416476Inferred only
CHRM5 participates in GPCR downstream signallingPathwayReactome R-HSA-388396Inferred only
CHRM5 participates in GPCR ligand bindingPathwayReactome R-HSA-500792Inferred only
CHRM5 participates in GPCRs class A rhodopsin likePathwayWikiPathways WP455Inferred only
CHRM5 participates in Monoamine GPCRsPathwayWikiPathways WP58Inferred only
CHRM5 participates in Muscarinic acetylcholine receptorsPathwayReactome R-HSA-390648Inferred only
CHRM5 participates in Regulation of actin cytoskeletonPathwayWikiPathways WP51Inferred only
CHRM5 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only

Show the remaining 2

CHRM5 participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only
CHRM5 regulates regulation of phosphatidylinositol dephosphorylationBiological processgene ontology P08912|GO:0060304Inferred only

Other names

1 name

Resolves to: CHRM5

Also called: Muscarinic acetylcholine receptor M5

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