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Proteins/UNIPROT:P08172
Muscarinic receptor for acetylcholine, a neurotransmitter found in the brain, neuromuscular junctions and the autonomic ganglia. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. CHRM2 is coupled to G(i)/G(o) (GNAI1 or GNAO1) G proteins and mediates signaling by inhibiting adenylate cyclase activity..
Function from UniProtKB (P08172), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
36 statements
36 statements · 4 reference databases · Subject: CHRM2 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
1 name
Resolves to: CHRM2