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Proteins/UNIPROT:P24386
Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation..
Function from UniProtKB (P24386), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
26 statements
26 statements · 2 reference databases · Subject: CHM · Sources: Hetionet, Reactome
6 names
Resolves to: CHM