Proteins/UNIPROT:P55291

CDH15

ProteinUNIPROT:P55291

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation.

Function from UniProtKB (P55291), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

autosomal dominant non-syndromic intellectual disability has a germline basis in CDH15DiseaseGenCC HGNC:1754|MONDO:0015802Inferred only

Statements

24 statements

24 statements · 3 reference databases · Subject: CDH15 · Sources: Hetionet, Reactome, WikiPathways

Order

ARHGAP45 covaries with CDH15ProteinHetionet hetionet:covaries:1013-23526Inferred only
EQTN covaries with CDH15ProteinHetionet hetionet:covaries:1013-54586Inferred only
ODAD4 covaries with CDH15ProteinHetionet hetionet:covaries:1013-83538Inferred only
PARM1 covaries with CDH15ProteinHetionet hetionet:covaries:1013-25849Inferred only
ARVCF interacts with CDH15ProteinHetionet hetionet:interacts:1013-421Inferred only
CDH15 interacts with BOCProteinHetionet hetionet:interacts:1013-91653Inferred only
CDH7 interacts with CDH15ProteinHetionet hetionet:interacts:1005-1013Inferred only
CDH9 interacts with CDH15ProteinHetionet hetionet:interacts:1007-1013Inferred only
CDH15 interacts with CDONProteinHetionet hetionet:interacts:1013-50937Inferred only
CDH15 interacts with CTNNA1ProteinHetionet hetionet:interacts:1013-1495Inferred only
CDH15 interacts with CTNNB1ProteinHetionet hetionet:interacts:1013-1499Inferred only
CDH15 interacts with GNA12ProteinHetionet hetionet:interacts:1013-2768Inferred only

Show the remaining 12

CDH15 interacts with JUPProteinHetionet hetionet:interacts:1013-3728Inferred only
CDH15 interacts with UBCProteinHetionet hetionet:interacts:1013-7316Inferred only
CDH15 participates in 22q11 2 copy number variation syndromePathwayWikiPathways WP4657Inferred only
CDH15 participates in Adherens junctions interactionsPathwayReactome R-HSA-418990Inferred only
CDH15 participates in Cell junction organizationPathwayReactome R-HSA-446728Inferred only
CDH15 participates in Cell-Cell communicationPathwayReactome R-HSA-1500931Inferred only
CDH15 participates in Cell-cell junction organizationPathwayReactome R-HSA-421270Inferred only
CDH15 participates in Developmental BiologyPathwayReactome R-HSA-1266738Inferred only
CDH15 participates in Hippo Merlin signaling dysregulationPathwayWikiPathways WP4541Inferred only
CDH15 participates in Hippo signaling regulationPathwayWikiPathways WP4540Inferred only
CDH15 participates in MyogenesisPathwayReactome R-HSA-525793Inferred only
CDH15 participates in Pleural mesotheliomaPathwayWikiPathways WP5087Inferred only

Other names

5 names

Resolves to: CDH15

Also called: Cadherin-14CDH14CDH3M-cadherinMuscle cadherin

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