Proteins/UNIPROT:Q9NRR3

CDC42SE2

ProteinUNIPROT:Q9NRR3

Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages..

Function from UniProtKB (Q9NRR3), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

14 statements

14 statements · 3 reference databases · Subject: CDC42SE2 · Sources: gene ontology, Hetionet, Reactome

Order

CDC42SE2 covaries with CPZProteinHetionet hetionet:covaries:56990-8532Inferred only
CDC42SE2 covaries with LMNB2ProteinHetionet hetionet:covaries:56990-84823Inferred only
CDC42SE2 covaries with TP73ProteinHetionet hetionet:covaries:56990-7161Inferred only
CDC42SE2 covaries with VPS37CProteinHetionet hetionet:covaries:55048-56990Inferred only
CDC42 interacts with CDC42SE2ProteinHetionet hetionet:interacts:56990-998Inferred only
RAC1 interacts with CDC42SE2ProteinHetionet hetionet:interacts:56990-5879Inferred only
UBC interacts with CDC42SE2ProteinHetionet hetionet:interacts:56990-7316Inferred only
CDC42SE2 participates in CDC42 GTPase cyclePathwayReactome R-HSA-9013148Inferred only
CDC42SE2 participates in RHO GTPase cyclePathwayReactome R-HSA-9012999Inferred only
CDC42SE2 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
CDC42SE2 participates in Signaling by Rho GTPasesPathwayReactome R-HSA-194315Inferred only
CDC42SE2 participates in Signaling by Rho GTPases, Miro GTPases and RHOBTB3PathwayReactome R-HSA-9716542Inferred only

Show the remaining 2

CDC42SE2 regulates regulation of Rho protein signal transductionBiological processgene ontology Q9NRR3|GO:0035023Inferred only
CDC42SE2 regulates regulation of signal transductionBiological processgene ontology Q9NRR3|GO:0009966Inferred only

Other names

3 names

Resolves to: CDC42SE2

Also called: CDC42 small effector protein 2Small effector of CDC42 protein 2SPEC2

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