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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:Q9NRJ3

CCL28

Protein·UNIPROT:Q9NRJ3

Open in the graph

Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner.

Function from UniProtKB (Q9NRJ3), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

19 statements

19 statements · 4 reference databases · Subject: CCL28 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

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ACKR2 interacts with CCL28ProteinHetionet hetionet:interacts:1238-56477Inferred only
CCR10 interacts with CCL28ProteinHetionet hetionet:interacts:2826-56477Inferred only
CCR3 interacts with CCL28ProteinHetionet hetionet:interacts:1232-56477Inferred only
CCL28 interacts with DDI1ProteinHetionet hetionet:interacts:414301-56477Inferred only
CCL28 participates in Chemokine receptors bind chemokinesPathwayReactome R-HSA-380108Inferred only
CCL28 participates in Chemokine signalingPathwayWikiPathways WP3929Inferred only
CCL28 participates in Class A/1 (Rhodopsin-like receptors)PathwayReactome R-HSA-373076Inferred only
CCL28 participates in Cytokine cytokine receptor interactionPathwayWikiPathways WP5473Inferred only
CCL28 participates in G alpha (i) signalling eventsPathwayReactome R-HSA-418594Inferred only
CCL28 participates in GPCR downstream signallingPathwayReactome R-HSA-388396Inferred only
CCL28 participates in GPCR ligand bindingPathwayReactome R-HSA-500792Inferred only
CCL28 participates in Immune infiltration in pancreatic cancerPathwayWikiPathways WP5285Inferred only

Show the remaining 7

CCL28 participates in Overview of proinflammatory and profibrotic mediatorsPathwayWikiPathways WP5095Inferred only
CCL28 participates in Peptide ligand-binding receptorsPathwayReactome R-HSA-375276Inferred only
CCL28 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
CCL28 participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only
CCL28 participates in T cell activation SARS CoV 2PathwayWikiPathways WP5098Inferred only
CCL28 regulates negative regulation of leukocyte tethering or rollingBiological processgene ontology Q9NRJ3|GO:1903237Inferred only
CCL28 regulates positive regulation of cell-matrix adhesionBiological processgene ontology Q9NRJ3|GO:0001954Inferred only

Other names

6 names

Resolves to: CCL28

Also called: CCK1MECMucosae-associated epithelial chemokineProtein CCK1SCYA28Small-inducible cytokine A28

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