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Proteins/UNIPROT:O00175

CCL24

Protein·UNIPROT:O00175

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Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3..

Function from UniProtKB (O00175), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

10 statements

10 statements · 3 reference databases · Subject: CCL24 · Sources: gene ontology, Hetionet, WikiPathways

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CCR3 interacts with CCL24ProteinHetionet hetionet:interacts:1232-6369Inferred only
CCL24 participates in Chemokine signalingPathwayWikiPathways WP3929Inferred only
CCL24 participates in Cytokine cytokine receptor interactionPathwayWikiPathways WP5473Inferred only
CCL24 participates in Overview of proinflammatory and profibrotic mediatorsPathwayWikiPathways WP5095Inferred only
CCL24 regulates positive regulation of actin filament polymerizationBiological processgene ontology O00175|GO:0030838Inferred only
CCL24 regulates positive regulation of angiogenesisBiological processgene ontology O00175|GO:0045766Inferred only
CCL24 regulates positive regulation of cell migrationBiological processgene ontology O00175|GO:0030335Inferred only
CCL24 regulates positive regulation of endothelial cell proliferationBiological processgene ontology O00175|GO:0001938Inferred only
CCL24 regulates positive regulation of inflammatory responseBiological processgene ontology O00175|GO:0050729Inferred only
CCL24 regulates regulation of cell shapeBiological processgene ontology O00175|GO:0008360Inferred only

Other names

8 names

Resolves to: CCL24

Also called: CK-beta-6Eosinophil chemotactic protein 2Eotaxin-2MPIF-2MPIF2Myeloid progenitor inhibitory factor 2SCYA24Small-inducible cytokine A24

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