Proteins/UNIPROT:Q16204

CCDC6

ProteinUNIPROT:Q16204

Acts as a structural scaffold that organizes free PP2Ac into a configuration that FBXO42 can recognize and ubiquitinate, leading to its proteasomal degradation. Also interacts independently with PPP4C through a mechanism distinct from FBXO42-mediated ubiquitination..

Function from UniProtKB (Q16204), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

13 statements

13 statements · 2 reference databases · Subject: CCDC6 · Sources: Hetionet, WikiPathways

Order

ATF2 interacts with CCDC6ProteinHetionet hetionet:interacts:1386-8030Inferred only
CSNK2A1 interacts with CCDC6ProteinHetionet hetionet:interacts:1457-8030Inferred only
HDAC1 interacts with CCDC6ProteinHetionet hetionet:interacts:3065-8030Inferred only
MAPK3 interacts with CCDC6ProteinHetionet hetionet:interacts:5595-8030Inferred only
PPP4C interacts with CCDC6ProteinHetionet hetionet:interacts:5531-8030Inferred only
UBC interacts with CCDC6ProteinHetionet hetionet:interacts:7316-8030Inferred only
CCDC6 participates in 16p11 2 proximal deletion syndromePathwayWikiPathways WP4949Inferred only
CCDC6 participates in Cancer pathwaysPathwayWikiPathways WP5434Inferred only
CCDC6 participates in Mesodermal commitment pathwayPathwayWikiPathways WP2857Inferred only
CCDC6 participates in Retinoblastoma gene in cancerPathwayWikiPathways WP2446Inferred only
CALU increases the expression of CCDC6ProteinHetionet hetionet:regulates:813-8030Inferred only
CD320 increases the expression of CCDC6ProteinHetionet hetionet:regulates:51293-8030Inferred only

Show the remaining 1

EIF4E increases the expression of CCDC6ProteinHetionet hetionet:regulates:1977-8030Inferred only

Other names

4 names

Resolves to: CCDC6

Also called: D10S170Papillary thyroid carcinoma-encoded proteinProtein H4TST1

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