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Proteins/UNIPROT:P57730

CARD18

Protein·UNIPROT:P57730

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Inhibits generation of IL-1-beta by interacting with caspase-1 and preventing its association with RIP2. Down-regulates the release of IL1B..

Function from UniProtKB (P57730), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

3 statements

3 statements · 2 reference databases · Subject: CARD18 · Sources: gene ontology, Hetionet

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CARD18 covaries with LCE3DProteinHetionet hetionet:covaries:59082-84648Inferred only
CARD18 regulates negative regulation of interleukin-1 beta productionBiological processgene ontology P57730|GO:0032691Inferred only
CARD18 regulates regulation of apoptotic processBiological processgene ontology P57730|GO:0042981Inferred only

Other names

3 names

Resolves to: CARD18

Also called: Caspase recruitment domain-containing protein 18Caspase-1 inhibitor IcebergICEBERG

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