Proteins/UNIPROT:Q9UF02

CACNG5

ProteinUNIPROT:Q9UF02

Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs). Modulates their gating properties by accelerating their rates of activation, deactivation and desensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity for GRIA1, GRIA4 and the long isoform of GRIA2. Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity)..

Function from UniProtKB (Q9UF02), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

7 statements

7 statements · 3 reference databases · Subject: CACNG5 · Sources: gene ontology, Hetionet, WikiPathways

Order

CACNG5 covaries with KCNK13ProteinHetionet hetionet:covaries:27091-56659Inferred only
CACNG5 covaries with NDUFS6ProteinHetionet hetionet:covaries:27091-4726Inferred only
TREX2 covaries with CACNG5ProteinHetionet hetionet:covaries:11219-27091Inferred only
CACNG5 participates in Arrhythmogenic right ventricular cardiomyopathyPathwayWikiPathways WP2118Inferred only
CACNG5 participates in MAPK signalingPathwayWikiPathways WP382Inferred only
CACNG5 regulates positive regulation of synaptic transmission, glutamatergicBiological processgene ontology Q9UF02|GO:0051968Inferred only
CACNG5 regulates regulation of AMPA receptor activityBiological processgene ontology Q9UF02|GO:2000311Inferred only

Other names

3 names

Resolves to: CACNG5

Also called: Neuronal voltage-gated calcium channel gamma-5 subunitTARP gamma-5Transmembrane AMPAR regulatory protein gamma-5

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