Proteins/UNIPROT:Q8IZS8

CACNA2D3

ProteinUNIPROT:Q8IZS8

The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Acts as a regulatory subunit for P/Q-type calcium channel (CACNA1A), N-type (CACNA1B), L-type (CACNA1C OR CACNA1D) but not T-type (CACNA1G) (By similarity)..

Function from UniProtKB (Q8IZS8), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

12 statements

12 statements · 4 reference databases · Subject: CACNA2D3 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

VPS37D covaries with CACNA2D3ProteinHetionet hetionet:covaries:155382-55799Inferred only
CACNA2D3 covaries with ZNF25ProteinHetionet hetionet:covaries:219749-55799Inferred only
ZNF354B covaries with CACNA2D3ProteinHetionet hetionet:covaries:117608-55799Inferred only
CACNA2D3 covaries with ZNF524ProteinHetionet hetionet:covaries:147807-55799Inferred only
CREB1 interacts with CACNA2D3ProteinHetionet hetionet:interacts:1385-55799Inferred only
LYL1 interacts with CACNA2D3ProteinHetionet hetionet:interacts:4066-55799Inferred only
CACNA2D3 participates in Arrhythmogenic right ventricular cardiomyopathyPathwayWikiPathways WP2118Inferred only
CACNA2D3 participates in MAPK signalingPathwayWikiPathways WP382Inferred only
CACNA2D3 participates in Neuronal SystemPathwayReactome R-HSA-112316Inferred only
CACNA2D3 participates in Presynaptic depolarization and calcium channel openingPathwayReactome R-HSA-112308Inferred only
CACNA2D3 participates in Transmission across Chemical SynapsesPathwayReactome R-HSA-112315Inferred only
CACNA2D3 regulates regulation of presynapse organizationBiological processgene ontology Q8IZS8|GO:0099174Inferred only

Other names

2 names

Resolves to: CACNA2D3

Also called: Voltage-dependent calcium channel subunit alpha-2/delta-3Voltage-gated calcium channel subunit alpha-2/delta-3

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