Proteins/UNIPROT:Q5T7M4

C1QTNF12

ProteinUNIPROT:Q5T7M4

Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue..

Function from UniProtKB (Q5T7M4), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

7 statements

7 statements · 3 reference databases · Subject: C1QTNF12 · Sources: gene ontology, Hetionet, WikiPathways

Order

MRPS5 covaries with C1QTNF12ProteinHetionet hetionet:covaries:388581-64969Inferred only
C1QTNF12 participates in 1p36 copy number variation syndromePathwayWikiPathways WP5345Inferred only
C1QTNF12 participates in CAMKK2 pathwayPathwayWikiPathways WP4874Inferred only
C1QTNF12 regulates negative regulation of gluconeogenesisBiological processgene ontology Q5T7M4|GO:0045721Inferred only
C1QTNF12 regulates positive regulation of D-glucose import across plasma membraneBiological processgene ontology Q5T7M4|GO:0046326Inferred only
C1QTNF12 regulates positive regulation of insulin receptor signaling pathwayBiological processgene ontology Q5T7M4|GO:0046628Inferred only
C1QTNF12 regulates regulation of D-glucose import across plasma membraneBiological processgene ontology Q5T7M4|GO:0046324Inferred only

Other names

11 names

Resolves to: C1QTNF12

Also called: ]Adipolin cleaved formAdipolin fCTRP12Adipolin full-length formAdipolin gCTRP12Adipose-derived insulin-sensitizing factorC1q and TNF related protein 12C1QDC2Complement C1q tumor necrosis factor-related protein 12CTRP12FAM132A

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