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Proteins/UNIPROT:Q13901
Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity)..
Function from UniProtKB (Q13901), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
25 statements
25 statements · 3 reference databases · Subject: C1D · Sources: gene ontology, Hetionet, Reactome
2 names
Resolves to: C1D