Proteins/UNIPROT:Q9P203

BTBD7

ProteinUNIPROT:Q9P203

Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression (By similarity)..

Function from UniProtKB (Q9P203), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

4 statements

4 statements · 2 reference databases · Subject: BTBD7 · Sources: gene ontology, Hetionet

Order

DDX53 covaries with BTBD7ProteinHetionet hetionet:covaries:168400-55727Inferred only
DICER1 covaries with BTBD7ProteinHetionet hetionet:covaries:23405-55727Inferred only
ZNF699 covaries with BTBD7ProteinHetionet hetionet:covaries:374879-55727Inferred only
BTBD7 regulates regulation of branching involved in salivary gland morphogenesisBiological processgene ontology Q9P203|GO:0060693Inferred only

Other names

2 names

Resolves to: BTBD7

Also called: BTB/POZ domain-containing protein 7KIAA1525

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