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Proteins/UNIPROT:P37288

AVPR1A

Protein·UNIPROT:P37288

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Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment..

Function from UniProtKB (P37288), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

26 statements

26 statements · 4 reference databases · Subject: AVPR1A · Sources: gene ontology, Hetionet, Reactome, WikiPathways

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ARRB2 interacts with AVPR1AProteinHetionet hetionet:interacts:409-552Inferred only
AVPR1A participates in Class A/1 (Rhodopsin-like receptors)PathwayReactome R-HSA-373076Inferred only
AVPR1A participates in Defective AVP does not bind AVPR1A,B and causes neurohypophyseal diabetes insipidus (NDI)PathwayReactome R-HSA-5619099Inferred only
AVPR1A participates in DiseasePathwayReactome R-HSA-1643685Inferred only
AVPR1A participates in Disorders of transmembrane transportersPathwayReactome R-HSA-5619115Inferred only
AVPR1A participates in G alpha (q) signalling eventsPathwayReactome R-HSA-416476Inferred only
AVPR1A participates in GPCR downstream signallingPathwayReactome R-HSA-388396Inferred only
AVPR1A participates in GPCR ligand bindingPathwayReactome R-HSA-500792Inferred only
AVPR1A participates in GPCRs class A rhodopsin likePathwayWikiPathways WP455Inferred only
AVPR1A participates in Peptide GPCRsPathwayWikiPathways WP24Inferred only
AVPR1A participates in Peptide ligand-binding receptorsPathwayReactome R-HSA-375276Inferred only
AVPR1A participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only

Show the remaining 14

AVPR1A participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only
AVPR1A participates in SLC transporter disordersPathwayReactome R-HSA-5619102Inferred only
AVPR1A participates in Vasopressin-like receptorsPathwayReactome R-HSA-388479Inferred only
AVPR1A regulates negative regulation of female receptivityBiological processgene ontology P37288|GO:0007621Inferred only
AVPR1A regulates negative regulation of transmission of nerve impulseBiological processgene ontology P37288|GO:0051970Inferred only
AVPR1A regulates positive regulation of cell growthBiological processgene ontology P37288|GO:0030307Inferred only
AVPR1A regulates positive regulation of cell population proliferationBiological processgene ontology P37288|GO:0008284Inferred only
AVPR1A regulates positive regulation of cytosolic calcium ion concentrationBiological processgene ontology P37288|GO:0007204Inferred only
AVPR1A regulates positive regulation of glutamate secretionBiological processgene ontology P37288|GO:0014049Inferred only
AVPR1A regulates positive regulation of heart rateBiological processgene ontology P37288|GO:0010460Inferred only
AVPR1A regulates positive regulation of prostaglandin biosynthetic processBiological processgene ontology P37288|GO:0031394Inferred only
AVPR1A regulates positive regulation of systemic arterial blood pressureBiological processgene ontology P37288|GO:0003084Inferred only
AVPR1A regulates positive regulation of vasoconstrictionBiological processgene ontology P37288|GO:0045907Inferred only
AVPR1A regulates regulation of systemic arterial blood pressure by vasopressinBiological processgene ontology P37288|GO:0001992Inferred only

Other names

5 names

Resolves to: AVPR1A

Also called: Antidiuretic hormone receptor 1aAVPR V1aAVPR1V1aRVascular/hepatic-type arginine vasopressin receptor

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