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Proteins/UNIPROT:Q53RT3

ASPRV1

Protein·UNIPROT:Q53RT3

Open in the graph

Protease responsible for filaggrin processing, essential for the maintenance of a proper epidermis organization..

Function from UniProtKB (Q53RT3), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

1 row

ichthyosis, lamellar, autosomal dominant has a germline basis in ASPRV1DiseaseGenCC HGNC:26321|MONDO:0007812Inferred only

Statements

8 statements

8 statements · 1 reference database · Subject: ASPRV1 · Sources: Hetionet

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ADM2 covaries with ASPRV1ProteinHetionet hetionet:covaries:151516-79924Inferred only
CYP2D6 covaries with ASPRV1ProteinHetionet hetionet:covaries:151516-1565Inferred only
ASPRV1 covaries with DHX58ProteinHetionet hetionet:covaries:151516-79132Inferred only
IL36A covaries with ASPRV1ProteinHetionet hetionet:covaries:151516-27179Inferred only
LYPD1 covaries with ASPRV1ProteinHetionet hetionet:covaries:116372-151516Inferred only
PIANP covaries with ASPRV1ProteinHetionet hetionet:covaries:151516-196500Inferred only
CUL2 interacts with ASPRV1ProteinHetionet hetionet:interacts:151516-8453Inferred only
UCHL5 interacts with ASPRV1ProteinHetionet hetionet:interacts:151516-51377Inferred only

Other names

6 names

Resolves to: ASPRV1

Also called: SASPSASPaseSkin aspartic proteaseSkin-specific retroviral-like aspartic proteaseTAPSTPA-inducible aspartic proteinase-like protein

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