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Proteins/UNIPROT:Q9H765
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits IFN-beta production through the IRF3 signaling pathway by targeting TBK1 via 'Lys-48'-linked ubiquitination, leading to its proteasomal degradation..
Function from UniProtKB (Q9H765), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
33 statements
33 statements · 2 reference databases · Subject: ASB8 · Sources: Hetionet, Reactome
2 names
Resolves to: ASB8