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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:A6NK59

ASB14

Protein·UNIPROT:A6NK59

Open in the graph

May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Plays a role in the inhibition of cardiomyocyte nuclear proliferation by mediating the ubiquitination and degradation of MAPRE2..

Function from UniProtKB (A6NK59), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

10 statements

10 statements · 2 reference databases · Subject: ASB14 · Sources: Hetionet, Reactome

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ASB14 covaries with PCDHB10ProteinHetionet hetionet:covaries:142686-56126Inferred only
ASB14 covaries with S100A2ProteinHetionet hetionet:covaries:142686-6273Inferred only
ASB14 covaries with WASHC2CProteinHetionet hetionet:covaries:142686-253725Inferred only
ASB14 participates in Adaptive Immune SystemPathwayReactome R-HSA-1280218Inferred only
ASB14 participates in Antigen processing: Ubiquitination & Proteasome degradationPathwayReactome R-HSA-983168Inferred only
ASB14 participates in Class I MHC mediated antigen processing & presentationPathwayReactome R-HSA-983169Inferred only
ASB14 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
ASB14 participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
ASB14 participates in NeddylationPathwayReactome R-HSA-8951664Inferred only
ASB14 participates in Post-translational protein modificationPathwayReactome R-HSA-597592Inferred only

Other names

2 names

Resolves to: ASB14

Also called: Ankyrin repeat and SOCS box protein 14ASB-14

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