Proteins/UNIPROT:Q6ZUM4

ARHGAP27

ProteinUNIPROT:Q6ZUM4

Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity)..

Function from UniProtKB (Q6ZUM4), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

12 statements

12 statements · 3 reference databases · Subject: ARHGAP27 · Sources: gene ontology, Hetionet, Reactome

Order

ARHGAP27 covaries with BDKRB1ProteinHetionet hetionet:covaries:201176-623Inferred only
CDC42 interacts with ARHGAP27ProteinHetionet hetionet:interacts:201176-998Inferred only
RAC1 interacts with ARHGAP27ProteinHetionet hetionet:interacts:201176-5879Inferred only
SH3KBP1 interacts with ARHGAP27ProteinHetionet hetionet:interacts:201176-30011Inferred only
UBC interacts with ARHGAP27ProteinHetionet hetionet:interacts:201176-7316Inferred only
ARHGAP27 participates in CDC42 GTPase cyclePathwayReactome R-HSA-9013148Inferred only
ARHGAP27 participates in RAC1 GTPase cyclePathwayReactome R-HSA-9013149Inferred only
ARHGAP27 participates in RHO GTPase cyclePathwayReactome R-HSA-9012999Inferred only
ARHGAP27 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
ARHGAP27 participates in Signaling by Rho GTPasesPathwayReactome R-HSA-194315Inferred only
ARHGAP27 participates in Signaling by Rho GTPases, Miro GTPases and RHOBTB3PathwayReactome R-HSA-9716542Inferred only
ARHGAP27 regulates regulation of small GTPase mediated signal transductionBiological processgene ontology Q6ZUM4|GO:0051056Inferred only

Other names

5 names

Resolves to: ARHGAP27

Also called: CAMGAP1CIN85-associated multi-domain-containing Rho GTPase-activating protein 1Rho-type GTPase-activating protein 27SH3 domain-containing protein 20SH3D20

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