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Proteins/UNIPROT:Q99965
Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein.
Function from UniProtKB (Q99965), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
5 statements
5 statements · 2 reference databases · Subject: ADAM2 · Sources: Hetionet, Reactome
8 names
Resolves to: ADAM2