Pathway
Transport of connexons to the plasma membrane
Following connexon oligomerization, the hemichannels must be transported to the plasma membrane. This has been shown to occur in transport vesicles called "cargo containers". Most of post-Golgi cargo containers have a diameter of of 50- 200 nm. Recently direct transport of connexins to GJ assembly sides has been described. Besides microtuble-dependent trafficking, a microtubule-independent delivery pathway may exist as concluded from studies using the secretory transport inhibitor, Brefeldin A (Musil and Goodenough 1993; De Sousa et al. 1993; Laird et al. 1995).
REACT:R-HSA-190872Reactome
What the reference databases state
Statements
19 statements
19 statements · 1 reference database · Subject: Transport of connexons to the plasma membrane · Sources: Reactome
- GJA1 participates in Transport of connexons to the plasma membraneProteinReactome R-HSA-190872Inferred only
- GJB2 participates in Transport of connexons to the plasma membraneProteinReactome R-HSA-190872Inferred only
- TUBA1A participates in Transport of connexons to the plasma membraneProteinReactome R-HSA-190872Inferred only
- TUBA1B participates in Transport of connexons to the plasma membraneProteinReactome R-HSA-190872Inferred only
- TUBA1C participates in Transport of connexons to the plasma membraneProteinReactome R-HSA-190872Inferred only
- TUBA3C participates in Transport of connexons to the plasma membraneProteinReactome R-HSA-190872Inferred only
- TUBA3D participates in Transport of connexons to the plasma membraneProteinReactome R-HSA-190872Inferred only
- TUBA3E participates in Transport of connexons to the plasma membraneProteinReactome R-HSA-190872Inferred only
- TUBA4A participates in Transport of connexons to the plasma membraneProteinReactome R-HSA-190872Inferred only
- TUBA8 participates in Transport of connexons to the plasma membraneProteinReactome R-HSA-190872Inferred only
- TUBAL3 participates in Transport of connexons to the plasma membraneProteinReactome R-HSA-190872Inferred only
- TUBB1 participates in Transport of connexons to the plasma membraneProteinReactome R-HSA-190872Inferred only
Show the remaining 7
- TUBB2A participates in Transport of connexons to the plasma membraneProteinReactome R-HSA-190872Inferred only
- TUBB2B participates in Transport of connexons to the plasma membraneProteinReactome R-HSA-190872Inferred only
- TUBB3 participates in Transport of connexons to the plasma membraneProteinReactome R-HSA-190872Inferred only
- TUBB4A participates in Transport of connexons to the plasma membraneProteinReactome R-HSA-190872Inferred only
- TUBB4B participates in Transport of connexons to the plasma membraneProteinReactome R-HSA-190872Inferred only
- TUBB6 participates in Transport of connexons to the plasma membraneProteinReactome R-HSA-190872Inferred only
- TUBB8 participates in Transport of connexons to the plasma membraneProteinReactome R-HSA-190872Inferred only