Pathway
Synthesis of CL
Cardiolipin(CL) is synthesized in the inner mitochondrial membrane, when phosphatidylglycerol (PG) and cytidine diphosphate-diacylglycerol (CDP-DAG) are converted into CL. In addition to be synthesized in mitochondria, CDP-DAG may also be imported from ER to serve as the cardiolipin precursor pool. PGP (phosphatidylglycerol phosphate) catalyzes rate limiting step of cardiolipin biosynthesis.
REACT:R-HSA-1483076Reactome
What the reference databases state
Statements
1 statement
1 statement · 1 reference database · Subject: Synthesis of CL · Sources: Reactome
- CRLS1 participates in Synthesis of CLProteinReactome R-HSA-1483076Inferred only