Pathway
NFE2L2 regulating inflammation associated genes
Subpathway representing inflammatory genes regulated by NFE2L2. NFE2L2 plays a pivotal role in regulating inflammation directly (by regulating inflammation-related genes like CCL2, IL8) and indirectly (through the HO-1-NFKB axis). This role of NFE2L2 plays a role in inflammatory diseases and expands NFE2L2 role beyond the antioxidant system.
REACT:R-HSA-9818026Reactome
What the reference databases state
Statements
5 statements
5 statements · 1 reference database · Subject: NFE2L2 regulating inflammation associated genes · Sources: Reactome
- CCL2 participates in NFE2L2 regulating inflammation associated genesProteinReactome R-HSA-9818026Inferred only
- CREBBP participates in NFE2L2 regulating inflammation associated genesProteinReactome R-HSA-9818026Inferred only
- EP300 participates in NFE2L2 regulating inflammation associated genesProteinReactome R-HSA-9818026Inferred only
- MAFK participates in NFE2L2 regulating inflammation associated genesProteinReactome R-HSA-9818026Inferred only
- NFE2L2 participates in NFE2L2 regulating inflammation associated genesProteinReactome R-HSA-9818026Inferred only