Pathway
Josephin domain DUBs
The Josephin domain is present in four human DUBs: Ataxin-3 (ATXN3), ATXN3L, Josephin-1 (JOSD1) and JOSD2. All have been shown to possess DUB activity. Josephin domain DUBs may specialize in distinguishing between polyubiquitin chains of different lengths.
REACT:R-HSA-5689877Reactome
What the reference databases state
Statements
12 statements
12 statements · 1 reference database · Subject: Josephin domain DUBs · Sources: Reactome
- ATXN3 participates in Josephin domain DUBsProteinReactome R-HSA-5689877Inferred only
- ATXN3L participates in Josephin domain DUBsProteinReactome R-HSA-5689877Inferred only
- JOSD1 participates in Josephin domain DUBsProteinReactome R-HSA-5689877Inferred only
- JOSD2 participates in Josephin domain DUBsProteinReactome R-HSA-5689877Inferred only
- PRKN participates in Josephin domain DUBsProteinReactome R-HSA-5689877Inferred only
- RAD23A participates in Josephin domain DUBsProteinReactome R-HSA-5689877Inferred only
- RAD23B participates in Josephin domain DUBsProteinReactome R-HSA-5689877Inferred only
- RPS27A participates in Josephin domain DUBsProteinReactome R-HSA-5689877Inferred only
- UBA52 participates in Josephin domain DUBsProteinReactome R-HSA-5689877Inferred only
- UBB participates in Josephin domain DUBsProteinReactome R-HSA-5689877Inferred only
- UBC participates in Josephin domain DUBsProteinReactome R-HSA-5689877Inferred only
- VCP participates in Josephin domain DUBsProteinReactome R-HSA-5689877Inferred only