Pathway
Caloric restriction and aging
Caloric restriction leads to a decrease in the ATP/AMP ratio, thereby activating the key nutrient sensor of the body: AMPK. AMPK then blocks mTOR function, as mTOR has an important role in regulat...
WP:4191
What the reference databases state
Statements
8 statements
8 statements · 1 reference database · Subject: Caloric restriction and aging · Sources: WikiPathways
- AKT1 participates in Caloric restriction and agingProteinWikiPathways WP4191Inferred only
- IGF1 participates in Caloric restriction and agingProteinWikiPathways WP4191Inferred only
- MTOR participates in Caloric restriction and agingProteinWikiPathways WP4191Inferred only
- NAMPT participates in Caloric restriction and agingProteinWikiPathways WP4191Inferred only
- PPARGC1A participates in Caloric restriction and agingProteinWikiPathways WP4191Inferred only
- PRKAB2 participates in Caloric restriction and agingProteinWikiPathways WP4191Inferred only
- SIRT1 participates in Caloric restriction and agingProteinWikiPathways WP4191Inferred only
- TP53 participates in Caloric restriction and agingProteinWikiPathways WP4191Inferred only