Catalyst

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
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Articles

Chemistry

Reactions
Reach

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Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

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Endpoint

24-hour urinary 5-hydroxyindoleacetic acid excretion

CAT:outcome/urinary-5-hiaa-24hreported in mg per 24 hours (or µmol per 24 hours, as reported)

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How it is measured

Urinary 5-hydroxyindoleacetic acid (5-HIAA) excreted in a complete 24-hour urine collection, quantified by the study's stated chemical or chromatographic assay.

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Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

Endpoint

24-hour urinary 5-hydroxyindoleacetic acid excretion

CAT:outcome/urinary-5-hiaa-24hreported in mg per 24 hours (or µmol per 24 hours, as reported)

Open in the graph

How it is measured

Urinary 5-hydroxyindoleacetic acid (5-HIAA) excreted in a complete 24-hour urine collection, quantified by the study's stated chemical or chromatographic assay.