Endpoint
Total Symptom Score (diabetic neuropathy)
CAT:outcome/total-symptom-score-diabetic-neuropathyreported in points
How it is measured
Total Symptom Score (TSS) of diabetic sensorimotor polyneuropathy: the sum of patient-rated frequency and severity of four positive neuropathic symptoms (stabbing pain, burning pain, paraesthesia, numbness) in the lower limbs, range 0 to 14.64, higher is worse, reported as the score or as the change from baseline. The recall period is recorded with each finding.