Endpoint
Serum beta-hydroxybutyrate
Butyric acid substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
CAT:outcome/serum-beta-hydroxybutyratereported in mmol/L
How it is measured
Serum, plasma or capillary whole-blood beta-hydroxybutyrate concentration by enzymatic assay or point-of-care ketone meter. Time since the last dose and fasting state are recorded with each finding; the excursion after medium-chain triglyceride or ketone-ester dosing peaks within 60 to 120 minutes and a fasted trough measures something else entirely.