Endpoint
Ovarian cancer incidence
CAT:outcome/ovarian-cancer-incidencereported in proportion1 finding from 1 compound
What moved it
How to read these marks1 finding · 1 compound · 1 null · by evidence strength
| Compound | Direction | Findings | Strongest evidence |
|---|---|---|---|
| α-tocopherol | no effect | 1 | Evidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers. |
Every finding here is a null result.
Measured, no effect detected
1 finding
α-tocopherol — no detected effect on
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.FindingNull result“Meta-analysis revealed that high category of total vitamin E intake had no significant effect on the risk of ovarian cancer (RRs = 0.95, 95%CIs = 0.78–1.16, I2 = 53.2%, P for heterogeneity = 0.019).”
Quoted verbatim from Association of vitamin E on the risk of ovarian cancer: a meta-analysis.. - Study
- meta-analysis
- Population
- Women in 11 observational studies (4 cohort, 7 case-control) comparing the highest versus lowest category of total vitamin E intake from food and supplements
Effect 0.95 risk ratio, 95% CI 0.78 to 1.16
Association of vitamin E on the risk of ovarian cancer: a meta-analysis.2019PMID:31774115Permalink
How it is measured
Incident ovarian cancer (ovarian carcinoma) diagnoses ascertained by cancer registry linkage, pathology report, self-report with confirmation, or medical record review, over the follow-up or recall window the source states.
Sources cited
1 paper
- Subject
- ovarian cancer incidence
- Findings
- 1
- Papers
- 1