Modified Rankin Scale 0-2 at 90 days (functional independence)

Method

Proportion of stroke patients scoring 0-2 on the modified Rankin Scale assessed 90 days after the index event, by a trained rater using a structured interview. Whether the assessment was blinded and whether it was made in person or by telephone recorded on the edge.

The method is part of the endpoint identity. Studies measuring the same quantity by a different method are held as separate endpoints.

Notes

SIGN INVERSION against the modified Rankin Scale 3-5 band at the same timepoint: both are proportions derived from the SAME scale in the SAME patients, but this band improves by RISING and the 3-5 band improves by FALLING. Mapping one onto the other inverts the finding precisely. Also distinct from the mRS 0-1 band, the 'excellent outcome' dichotomy, which is a strictly narrower cut of the same scale, yields smaller proportions, and frequently gives a different treatment effect — the cut-point is not interchangeable and both must never be counted from one trial as separate evidence. The ordinal shift analysis across all seven levels is a third endpoint again.