Endpoint
Helicobacter pylori eradication rate
CAT:outcome/h-pylori-eradication-ratereported in proportion (pooled as absolute risk difference or odds ratio)1 finding from 1 compound
What moved it
How to read these marks1 finding · 1 compound · 1 null · by evidence strength
| Compound | Direction | Findings | Strongest evidence |
|---|---|---|---|
| Lactiplantibacillus plantarum | no effect | 1 | Evidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers. |
Every finding here is a null result.
Measured, no effect detected
1 finding
Lactiplantibacillus plantarum — no detected effect on
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.FindingNull result“Although a numerically higher eradication rate was observed in the Lp05 group, the difference was not statistically significant (χ2 = 0.349, P = 0.555).”
Quoted verbatim from Adjuvant Lactiplantibacillus plantarum Lp05 modulates gut microbiota and alleviates symptoms during Helicobacter pylori eradication.. - Study
- RCT
- Duration
- 6 weeks
- Dose
- 1 x 10^11 CFU per day, with bismuth quadruple therapy for 2 weeks then alone for 4 weeks
- Population
- Symptomatic Helicobacter pylori-positive adults aged 18-65 given bismuth quadruple therapy for 2 weeks in both arms; trial completers (34 per arm); dextrin placebo in the comparator arm
Adjuvant Lactiplantibacillus plantarum Lp05 modulates gut microbiota and alleviates symptoms during Helicobacter pylori eradication.2026PMID:42117710Permalink
How it is measured
Proportion of treated patients confirmed free of Helicobacter pylori infection on post-treatment testing (urea breath test, stool antigen test, or histology at a stated interval after therapy). The analysis population the source used is recorded with each finding.
Sources cited
1 paper
- Subject
- helicobacter pylori eradication rate
- Findings
- 1
- Papers
- 1