Endpoint
FEV1 area under the curve 0 to 6 hours
CAT:outcome/fev1-auc-0-6hreported in L
How it is measured
Area under the time curve of forced expiratory volume in one second from serial spirometry over the first six hours after a dose, normalised to the time window, as change from baseline. Reported as litres. The dose day or week of the measurement is recorded with each finding.