Endpoint
Disease Activity Score in 28 joints (DAS-28)
CAT:outcome/das-28reported in score1 finding from 1 compound
What moved it
How to read these marks1 finding · 1 compound · by evidence strength
| Compound | Direction | Findings | Strongest evidence |
|---|---|---|---|
| curcumin | down | 1 | Evidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers. |
Reported to move it
1 finding
curcumin — decreases
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“The pooled analysis demonstrated that curcumin supplementation significantly reduced DAS28 compared with controls (WMD = –1.47, 95% CI [–1.68,–1.26]) (Fig. A).”
Quoted verbatim from Effect of curcumin on inflammatory markers and disease activity in patients with rheumatoid arthritis: A meta-analysis.. - Study
- meta-analysis
- Population
- adults with rheumatoid arthritis
Effect -1.47 mean difference, 95% CI -1.68 to -1.26
Effect of curcumin on inflammatory markers and disease activity in patients with rheumatoid arthritis: A meta-analysis.2025PMID:41327719Permalink
How it is measured
Disease Activity Score in 28 joints: a weighted composite of the 28-joint tender count, the 28-joint swollen count, an acute-phase reactant, and the patient global assessment on a visual analogue scale. Whether the reactant is ESR or CRP is recorded with each finding and is not optional — DAS28-ESR and DAS28-CRP differ systematically by roughly a third of a point and are not interchangeable.
Sources cited
1 paper
- Subject
- disease activity score in 28 joints (das-28)
- Findings
- 1
- Papers
- 1