Endpoint
Type II collagen degradation marker (CTX-II)
CAT:outcome/collagen-type-ii-degradation-markerreported in ng/mmol creatinine or ng/mL
How it is measured
C-terminal crosslinked telopeptide of type II collagen, by immunoassay in urine (usually normalised to creatinine) or in serum. Matrix and normalisation recorded with each finding. Reflects cartilage collagen breakdown.