Endpoint
Charcot-Marie-Tooth Neuropathy Score (CMTNS)
CAT:outcome/cmt-neuropathy-scorereported in points (score)
How it is measured
Total score on the Charcot-Marie-Tooth Neuropathy Score, a clinician-rated composite impairment score for Charcot-Marie-Tooth disease summing nine items (sensory symptoms, motor symptoms, pin sensibility, vibration, strength of arms and legs, and ulnar CMAP and sural SNAP amplitudes from nerve conduction studies), scored 0 to 36 in the original version, higher is worse. Reported as the score at a timepoint or as the change from baseline over a stated interval. The version (original 9-item CMTNS or the second-edition CMTNS2 with rasch-weighted items) is recorded with each finding.