Endpoint

Calcineurin-inhibitor nephrotoxicity incidence

CAT:outcome/calcineurin-inhibitor-nephrotoxicity-incidencereported in risk ratio

How it is measured

Proportion of ciclosporin- or tacrolimus-treated patients with clinician-adjudicated calcineurin-inhibitor nephrotoxicity - a sustained renal function decline attributed to the drug, with or without histological confirmation of arteriolar hyalinosis or striped interstitial fibrosis.