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Catalyst

(R)-carnitineFinding

(R)-carnitine decreases HOMA-IR

lowersVery limited evidenceFindingreplicated ×1

01 · The sentence it was drawn from

“Carnitine supplementation significantly reduced fasting blood sugar (FBS; WMD -2.93 mg/dL, 95 % CI -5.20 to -0.65), fasting insulin (WMD -3.54 μU/mL, 95 % CI -7.00 to -0.07), and HOMA-IR (WMD -0.69, 95 % CI -1.26 to -0.13), but had no significant effect on QUICKI.”
Quoted verbatim from Effects of carnitine supplementation on glycemic markers in women with overweight and obesity: A systematic review and meta-analysis of randomized controlled trials.
This finding among the 63 findings on its endpoint

(R)-carnitine

HOMA-IR

lowers

Effect as reported

−0.69mean difference

CI −1.26 to −0.13

Who
Women with overweight or obesity in eight studies (nine randomized trial arms), versus placebo
Dose studied
not reported

Very limited evidencePMID 41177307 · 2025

02 · The study

Study
meta-analysis
Duration
not reported

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limitedthis finding
  • insufficient

03 · The paper

Diabetes research and clinical practice
What else it reported2 findings · 1 compound · 2 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M701EH8DWK9QWQGJ0M6FMF5Q