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Catalyst

(R)-carnitineFinding

(R)-carnitine increases HDL cholesterol

raisesVery limited evidenceFindingreplicated ×1

01 · The sentence it was drawn from

“The pooled results indicated that L-carnitine administration led to a significant decrease in triglycerides (WMD: -10.35; 95% CI: -16.43, -4.27), total cholesterol (WMD: -9.47; 95% CI: - 13.23, -5.70) and LDL-cholesterol (LDL-C) concentrations (WMD: -6.25; 95% CI: -9.30, -3.21), and a significant increase in HDL-cholesterol (HDL-C) levels (WMD: 1.39; 95% CI: 0.21, 2.57).”
Quoted verbatim from The Effects of L-Carnitine Supplementation on Serum Lipids: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This finding among the 93 findings on its endpoint

(R)-carnitine

HDL cholesterol

raises

Effect as reported

1.39mean difference

CI 0.21 to 2.57

Who
Patients and healthy individuals in 67 randomized controlled trials
Dose studied
not reported

Very limited evidencePMID 31470778 · 2019

02 · The study

Study
meta-analysis
Duration
not reported

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limitedthis finding
  • insufficient

03 · The paper

Current pharmaceutical design
What else it reported4 findings · 1 compound · 4 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M701EBGQ63S7GCK8K96AZ45F